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1. Glucosamine Sulfate -
This is the most fundamental and natural component of our joint cartilage, tendons, bone, ligament, nails, hair, etc. There are multiple clinical studies and published reports proving its value in reducing symptoms and rebuilding the damaged cartilage of your joints. Our own body's cartilage cells use for repair of joint as well as inhibits enzymes that destroy cartilage. Capable of increasing flexibility and resistance to corrosion to counteract joint stress, Dr. Phoon reported its unique ability to repair cartilage and damaged joints. By blocking the destructive mechanism of cartilage degeneration, glucosamine can halt and even reverse the disease process and relieves symptoms. However, beware that there are several forms of glucosamine, all clinical studies have used only one kind, don't buy the wrong one just because it is cheaper but doesn't work. Helme et al clinical study of 68 pts. With knee joint arthritis, loading pain improved by 80%.
2. MSM (Methyl Sulfonyl Methane) -
This is critical sulfur required for proper repair of injured cartilage, ligaments and tendons. Although naturally present in our food like vegetables, fruits, fish and meats, it is not available at sufficient quantities for our joint needs (Qie et al, 1998). Reports show that a strategic use of MSM increases the therapeutic efficiency of glucosamine because of the sulfur presence. This combination really works. Dr. Lawrence UCLA Medical School found 80% arthritis points improved their pain symptoms.
3. Ginger -
Often overlooked and forgotten. This is one of the oldest anti-inflammatory and pain reliever known to mankind. Using a special concentrated extract of gingerol (the active ingredient) is proven very effective at relieving arthritis pain. The Journal of Osteoarthritis Cartilage reports Israel's Tel Aviv University studied 29 patients suffering from osteoarthritis of the knee, half received ginger extract, the other half a fake placebo. At the end of 12 weeks, the ginger group showed knee pain reduced significantly and joint mobility increased significantly.
Another study at University of Miami enrolled 247 subjects with severe osteoarthritis of the knee subjects were divided into ginger group and placebo for six weeks. Sixty three (63%) of the ginger extract group improved significantly while the placebo group showed no improvement. Ginger group showed twice as much improvement in pain after walking test. Journal of Arthritis and Rheumatism Nov 2001.
Dr. Patrick Nassey MD. Reported in Chicago Daily Herald 3/15/04 that Ginger maybe the alternative approach to reduce arthritis of the knee.
At a University study in Denmark, Dr. Srivastava reported 56 patients comprised of Rheumatoid Arthritis, Osteoarthritis, and muscle spasm pain. Using Ginger, 75% of arthritis experienced relief of pain and swelling. All of the patients with muscular pain experienced relief and most importantly, no side effects were reported after several months to several years of consumption. Med Hypothesis Dec 1992.
4. Grape Skin -
This unique supplement is very misunderstood. Magazines and catalogs try to sell you a lower quality grape seed for its content of active ingredient Resveratrol, but scientific evidence disputes this kind of salesmanship. Research performed on quantitative analysis by Xingjian Medical School, one of the great medical schools in Asia, clearly shows that contents of Resveratrol are much higher on grape skin of winery followed by fresh grape skin and last in Resveratrol content in grape seeds. Published by Dr. Xiang on Sept 2003. This research was confirmed Dr. Careri Published in Journal Agricultural Food Chem Aug 2003. University of Parma, Italy.
Resveratrol is particularly able to neutralize the destructive COX-2 enzyme that causes inflammation and pain of the joint and muscle. From research by Michigan State University. Published in Journal of Agricultural Food Chem Jan 2004.
This unique ingredient is very rarely used in pain formulation because research and information has just become available to the public. The copy cats will surely have much to catch up here.
5. Quercetin -
This very rare ingredient and even more unusual usage as the "ultimate weapon" against inflammation. Quercetin is the champion of anti-inflammation reported by Dr. Morikawa from Sagami Women's University in Japan wonderful laboratory cell microscopy proof of Quercetin suppression of inflammatory response in animals studies published in Life Science Dec 2003.
An even greater technology breakthrough reported by Dr. Woo from Chubu University that Quercetin is able to suppress bone loss which may stop cartilage degeneration published in Biol. Pharma Bul 2004.
6. Boswellia Serrata -
This anceint ayuverdic herb of Frankincense has been used as anti-inflammatory for a thousand years. Bosswella acid the active ingredient has beenfound
This ancient Ayuverdic herb of Frankincense has been used as anti-inflammatory for a thousand years. Boswellia acid the active ingredient has been found to block the destructive leukotrienes enzymes which trigger painful inflammation.
Recently at University of Poona, India, researchers report 42 severely arthritic patients failed to respond to prescription medication, after 3 months of Boswellia extracts they experienced significant decrease in joint pain, joint swelling, and stiffness. They began to have improvements in the first 2 to 4 weeks.
Dr. Kimmatkar reported in J. Phytomedicine Jan 2003. that his clinical study double blind, placebo controlled 30 patients showed 100% success in decrease of knee pain, increased knee flexibility and increased walking distance. Dr. Amon of University Tubingen, Germany went even further to report Boswellic acid improved not only rheumatoid arthritis, but also chronic colitis, ulcerative colitis, Crohn's disease, even bronchial asthma. The famous Dr. Andrew Weil, MD. Recommends Boswellia herb for inflammatory conditions such as chronic fibromyalgia and Prostatitis.
7. Curcumin -
One of the finest anti-inflammatory herbs in the natural arsenal. Very special because of its unique ability to inhibit and neutralize both destructive enzyme the 5-LO from Leukotrienes as well as COX-2 who are the main culprits in the fire of inflammation and pain. J. Ethropharamacology March 1993.
Also against Neurodegenerative disease as COX-2 produce further prostaglandins during episodes of inflammation. Dr. Kaug, J. Parmacol. March 2004 confirms that curcumin indeed "significantly inhibit" destructive enzyme COX-2. Curcumin even protects against colon cancer, according to Dr. Goel published Cancer Letter 2001. According to Dr. Susan Lark, a study published by the American J. of Natural Medicine. Reported curcumin was able to reduce morning stiffness and swelling as comparable to cortisone and phenylbutazone, without the side effects.
8. White Willow -
Centuries old this natural remedy provided pain relief for all conditions. It is the grand father of all analgesics and pain pills with a number of strong clinical and proven efficacies as reported by Dr. Chrubasik in his research on Pain Management published in German Wein Med 2002.
In Summary:
Bad enzymes causing inflammation and pain are COX-2 and Leukotrienes (5 LO). Good enzymes COX-1 protects your stomach from ulcers and normalize body balance functions•
Pinpoint & Eliminate Destructive causes of joint pain
• Restore joint flexibility
• Stop your dependence on Dangerous Pharmaceutical Drugs
• Relief from pain & inflammation
• Halt the destruction of your joints
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